Vyper build guide

Rey's Compy Wizard Lizard (GUIDED!)

by Rey The Pastel PuppygirlVersion 187Updated Sep 30, 2026Guide #196233

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Observed usage

Match statistics · filters applied except game mode

Published guide

As written by the author · latest version · not affected by filters

In-game favourites: 29,455 (as last synced by the API; not match usage)

Author's notes

Deal 1050 GUARANTEED and INSTANT damage at 4.8k SOULS!!!! STILL GET ALMOST AS HIGH GUN DPS ALL GAME BTW Nuke with spirit damage and gun damage at the same time!! Rush 4.8k spirit spike to absolutely nuke with the 2! Use her ult 1 second after her 2 to both confirm the kill its extra damage and also prevent them from using an ability to dodge the venom!

Item categories

1Lane
Author's category · 7 items · discord.gg/YhxqADYst7 We play 6 stacks and customs very often!
1. 1
  Extra Spirit
2. 2
  Improved Spirit
  Built from Extra Spirit
  nuclear barrels
3. 3
  Quicksilver Reload
  Reloads gun and extra damage on dagger
4. 4
2Early game
Game stage · 4 items · CORRUPT YOUR BURST FIRE = INFINITE SLIDE
1. 1
  Bullet Lifesteal
  Sustain
2. 2
  Enduring Speed
3. 3
  Spirit Lifesteal
4. 4
3pick ONE (in order of my prefrence)optional
Author's category · 3 items
1. 1
  Point Blank
  Built from Close Quarters
  The Slow and Damage are really good. This is what I buy 80% of games
2. 2
  Toxic Bullets
  Buy this if they have a bunch of tanks
3. 3
  Blood Tribute
  High skill floor item with really good value
4Mid-Late Game
Author's category · 3 items
1. 1
  Mercurial Magnum
  Built from Quicksilver Reload
  Once you get this start farming t3 camps
2. 2
  Leech
  Built from Bullet Lifesteal
  Start taking fights after you get this
3. 3
  Spiritual Overflow
  Built from Spirit Lifesteal
  This item keeps getting buffed. Good for buffing both of our damage types
5Ultra Late Game
Author's category · 4 items · Buy which you need, no order
1. 1
  Frenzy
  Comes with bullet lifesteal and fire rate while also making you a lot stronger below half hp. The debuff resist is really good.
2. 2
  Ricochet
  REALLY good when the enemy keeps deathballing or grouping up in fights
3. 3
  Unstoppable
  Good for dodging stuns that would get you killed
6Other Strong Itemsoptional
Author's category · 10 items · Subscribe to ReyThePastel on youtube!
1. 1
  Bullet Resist Shredder
  Can be bought instead of cold front
2. 2
  Escalating Resilience
  DPS boost AND big resistance. You get full resitance almsot immediatly so its basically a better Bullet Resilience as an orange item
3. 3
  Swift Striker
7SCROLL DOWN FOR BUILD GUIDE | SCROLL DOWN FOR BUILD GUIDE | SCROLL DOWN FOR BUILD GUIDE | SCROLL DOWN FOR BUILD GUIDEoptional
Author's category · 11 items
1. 1
  Reactive Barrier
  can be a life savor in lane, especially against bebop
2. 2
  Dispel Magic
  I often buy this to remove anti heals, especially spirit burn
3. 3
  Metal Skin
8Lane Strategy: You want to be focusing your damage on one target. Try getting the weaker enemy down to low health for your venom. You daggers can do a lot of damage if you can hit three in a row on one target. When you unlock ult your instakill threeshold will be at 700 damage. You get 400 damage from direct hit ult and 300 damage from venom. You also can bring it up to 840 kill threshold if you land a dagger first! After Coldfront (4.8k spirit spike): If you hit coldfront then dagger then venom then ult you will deal 1000 damage. (MAKE SURE TO USE VENOM 1 SECOND BEFORE ULT IF THE ENEMY HAS AN ABILITY THAT LETS THEM DODGE. [Like pocket suitcase or dynamo teleport])
Author's category · 0 items
No items listed.
9Lane Building: if the enemy is on a hero that has a lot of healing (like Mo and Krill) then you can get t2 venom before t2 ult. DO NOT BUY RAPID ROUNDS UNLESS YOU PLAN ON BUYING POINTBLANK. You can buy your 4.8k gun spike before buying your 4.8k green spike if you feel like it will help you get more kills.
Author's category · 0 items
No items listed.
10Mid Game Strategy: Roam around taking t2 camps while looking for enemies low on health to execute. Your main role is to execute low health enemies with your venom and ult. Pay lots of attention to the minimap and don't get killed while in the jungle. As soon as you buy Mercurial Magnum you can start farming the t3 camps. Once you get Leech you can start taking fights really well and you should be looking to get kills. Burst fire helps round out your consistant damage and mobility.
Author's category · 0 items
No items listed.
11Mid Game Building: The general pick for your t3 gun item is Point Blank. Thats what I usually buy. However when the enemy team has 2 tanks I will buy toxic bullets. Sometimes when the enemy team has a lot of stuns or Damge over Times I will get blood tribute to reduce them. If you didnt buy pointblank, you can consider buying it after you buy burst fire. Otherwise you can sell close quarters in late game for better items.
Author's category · 0 items
No items listed.
12Late Game Strategy: Once the game starts getting late, our venom+ult combo isnt quite as effective because of the high health pools. So start focusing on dealing high amounts of gun damage to one target at a time and then using our ult and venom to guarantee the kill. As the game goes on longer it becomes easier to counter Vyper so you have to adapt your items to the gamestate. Going full into gun damage can work against some players, but often times (especially in higher rank) most people will buy items that instantly counter this like metalskin and return fire. This is why building half into spirit damage and debuffs can make much more impact in super late game then just full into gun.
Author's category · 0 items
No items listed.
13Late Game Building: Late game either start buying strong t4 items or resistances. If you are dying quickly consider buying the Resilience items (Escalating Resilience is better than Bullet Resilience on vyper). I usually buy Spiritual Overflow first for all the stats it gives and then I either buy Frenzy or Ricochet. Sometimes its hard to get good value in super late game fights so I will very very often buy Silencer and Inhibitor to reduce the enemies damage by 50% to my team!
Author's category · 0 items
No items listed.

Categories appear in the author's order. Only the editor's default Early, Mid and Late sections are marked as game stages; the author's own categories keep their names. “Built from” links come from the game's item recipes.

Published ability order

Published ability order: unlocks and upgrades in the author's order, one row per ability in slot order
Screwjab DaggerScrewjab Dagger	Screwjab Dagger: Ability unlocked, step 1													Screwjab Dagger: 1 AP upgrade, step 14	Screwjab Dagger: 2 AP upgrade, step 15