Vyper build guide

Amatis' Snake Hybrid of ALL TIME! (1000% winrate)

by AmatisVersion 17Updated Sep 6, 2026Guide #467301

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Observed usage

Match statistics · filters applied except game mode

Published guide

As written by the author · latest version · not affected by filters

In-game favourites: 7,665 (as last synced by the API; not match usage)

Author's notes

Everything is Annotated!! I fixed it so now it looks nice again. Sorry about that. "Ew hybrid vyper ew!" There is plenty of gun here, dont worry. I'd let Vyper hold me close and if she stabbed me, that'd be just okay with me. "hi" - Digital

Item categories

1Lane!
Author's category · 9 items · Try and focus both 4.8k spikes
1. 1
  Extra Spirit
  Bonus spirit is nice. It also makes pokes with the dagger a bit better
2. 2
  Improved Spirit
  Built from Extra Spirit
  Same as Extra Spirit, just more so
3. 3
  Quicksilver Reload
  Saves you from needing to reload, and increases dagger damage
4. 4
2Mid to Late!
Author's category · 4 items
1. 1
  Burst Fire
  Built from Rapid Rounds
  More sliding and more shooting, best of both worlds!
2. 2
  Mercurial Magnum
  Built from Quicksilver Reload
  Powerspike, get this early as possible!!
3. 3
  Point Blank
  Built from Close Quarters
  Goes great with weighted shots since you want them in front of you, not able to leave
3Sustain
Author's category · 2 items · Pick 1
1. 1
  Vampiric Burst
  Built from Bullet Lifesteal
  Leech is more consistent but VB provides a huge burst in lifesteal
2. 2
  Leech
  Built from Bullet Lifesteal
  Leech is really consistent and easier to use. Though you should get used to using actives!! They are useful!!!!
4If you dont know what 4.8k spike is: At the bottom left of your screen there are 3 bars (Weapon, Vitality, Spirit). The more you invest into a category the more bonuses youll get. At 4.8k the bonus 'spikes', giving you a nice increase to your stats in that category
Author's category · 0 items
No items listed.
5Early Green Stuff!optional
Author's category · 8 items · You are so green!
1. 1
  Healing Rite
  A pick-me-up in case things get rough
2. 2
  Rebuttal
  For the people who just can't stop pressing Q (or Viscous)
3. 3
  Healbane
  For any nerds with lifesteal (not us though, its cool when we do it)
6Very Late Game!optional
Author's category · 8 items · Preference really
1. 1
  Ricochet
  Ricochet will proc all of your bullet items on everyone it ricochets to, making it great for Silencer/Venom
2. 2
  Silencer
  Pairs beautifully with Ricochet
3. 3
  Spiritual Overflow
  A great pick for any hybrid vyper mains!
7Later Green Stuff!
Author's category · 6 items · Still so green!
1. 1
  Spirit Resilience
  At some point youll come across a team that does nasty spirit damage. This is an overall great card for that
2. 2
  Bullet Resilience
  And at some point youll also come across a nasty gun team, this is also a great overall counter for that.
3. 3
  Counterspell
  Rem/Apollo/Lash/Talon ult, Bebop/Seven bombs
8Debuff Junk!optional
Author's category · 11 items · T2 purples can replace Bullet Resist Shredder
1. 1
  Rusted Barrel
  Wraith Haze or Infernus Lane
2. 2
  Spirit Sap
  "god i hate people who just nuke you constantly, people like holliday or doorman its so annoying"
3. 3
  Cold Front
  Slows people and does a nice burst of damage. Good for people who try poking you and pulling back instantly
9test
Author's category · 2 items · im testing this, you can ignore
1. 1
  Arcane Surge
  Grab instead of BRS(?)
2. 2
  Siphon Bullets
10Street Brawl Imbues
Author's category · 4 items · You can ignore this
1. 1
  Ballistic Enchantment
2. 2
  Surge of Power
  Built from Extra Spirit
3. 3
  Mystic Expansion
4. 4

Categories appear in the author's order. Only the editor's default Early, Mid and Late sections are marked as game stages; the author's own categories keep their names. “Built from” links come from the game's item recipes.

Published ability order

Published ability order: unlocks and upgrades in the author's order, one row per ability in slot order
Screwjab DaggerScrewjab Dagger	Screwjab Dagger: Ability unlocked, step 1													Screwjab Dagger: 1 AP upgrade, step 14	Screwjab Dagger: 2 AP upgrade, step 15