Vyper build guide
by StrikeVersion 12Updated May 1, 2026Guide #599314
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Stuff for Vyper based on popular builds, and top items from Ascendant / Eternus. (No, I'm not either rank.)
1Lane:
Author's category · 10 items · Prioritize 4.8k Spirit + Opening Rounds. Buy others as needed.
Extra Spirit
Poking power.
Improved Spirit
Built from Extra Spirit
Potent poking.
Quicksilver Reload
Less reloads, more dagger damage. Prerequisite.
Slowing Hex
Helps land a lot of damage, plus removes escape options.
High-Velocity Rounds
Opening Rounds
Built from High-Velocity Rounds
Helps with maximizing Lethal Venom.
Intensifying Magazine
Quicksilver Reload + Slide Shooting should make this easy to have up.
Rapid Rounds
Basic fire rate bonus.
Swift Striker
Built from Rapid Rounds
If you need to get gun spike quickly.
Extra Stamina
Gonna need more stamina for slidnig.
2Early Greens
Author's category · 4 items · For later stuff.
Healing Rite
For pretty rough lanes.
Extra Health
Basic health for Fortitude.
Bullet Lifesteal
Initial item for the IV items.
3Mid:
Author's category · 2 items · Mercurial Magnum.
Stamina Mastery
Built from Extra Stamina
Movement is necessary.
Mercurial Magnum
Built from Quicksilver Reload
Single target shredding.
4Late:
Author's category · 5 items · Small Gun investments. Start shredding.
Burst Fire
Built from Rapid Rounds
Good item to slide and shoot with.
Point Blank
For very close engagements.
Tesla Bullets
For faster farming.
5Late Greens
Author's category · 3 items
Vampiric Burst
Built from Bullet Lifesteal
You can potentially spam the +75% Ammo while out of combat; no need to slide with a bunch of ammo.
Leech
Built from Bullet Lifesteal
General item for overall damage plus healing.
Siphon Bullets
Gun item in disguise.
6Too Late:
Author's category · 5 items · Big gun investments. Kill everything.
Capacitor
Built from Tesla Bullets
Better wave clear, also used to silence.
Boundless Spirit
Built from Improved Spirit
Powerspike x2. Stronger Venom. Can be sold later on when spirit damage becomes obsolete.
Lucky Shot
Piece for more damage.
7I Hate CCoptional
Author's category · 6 items
Rebuttal
For the people who just can't stop pressing Q
Reactive Barrier
Dispel Magic
Gets rid of Disarm, also great for Bebop Bombs
8Anti-Healoptional
Author's category · 3 items
Healbane
For any nerds with lifesteal (not us though, its cool when we do it)
Inhibitor
Better Healbane
Crippling Headshot
Resistance and Anti-heal is nice, though landing headshots may be tricky for some (me)
9Spirit Problemsoptional
Author's category · 3 items
Spirit Shielding
Spirit Resilience
Spellbreaker
For anyone who does crazy spirit burst like Grey Talon
10Ability Problemsoptional
Author's category · 3 items
Silence Wave
Knockdown
Focus Lens
11Extra Items Here For Situationsoptional
Author's category · 5 items · May or may not be good.
Battle Vest
Bullet Resist Shredder
Disarming Hex
Categories appear in the author's order. Only the editor's default Early, Mid and Late sections are marked as game stages; the author's own categories keep their names. “Built from” links come from the game's item recipes.
Screwjab DaggerScrewjab Dagger | Screwjab Dagger: Ability unlocked, step 1 | Screwjab Dagger: 1 AP upgrade, step 14 | Screwjab Dagger: 2 AP upgrade, step 15 |
|---|
Fortitude
Built from Extra Health
Keeps you in the field longer instead of going back to base.
Ricochet
Multi-target shredding.
Glass Cannon
x2 Damage shredding. Buy if very scaled.
Silencer
A green item in disguise.
Spiritual Overflow
Fire Rate + Spirit Power.
Counterspell
Unstoppable
Indomitable
Built from Reactive Barrier
Some crazy new item...
Armor Piercer
Built from High-Velocity Rounds
Sadly with the 4/30 patch, this doesn't penetrate through armor...
Shadow Weave
Meme item.
| Screwjab Dagger: 5 AP upgrade, step 16 |
Lethal VenomLethal Venom | Lethal Venom: Ability unlocked, step 2 | Lethal Venom: 1 AP upgrade, step 3 | Lethal Venom: 2 AP upgrade, step 9 | Lethal Venom: 5 AP upgrade, step 10 |
|---|
SlitherSlither | Slither: Ability unlocked, step 4 | Slither: 1 AP upgrade, step 5 | Slither: 2 AP upgrade, step 8 | Slither: 5 AP upgrade, step 11 |
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Petrifying BolaPetrifying Bola | Petrifying Bola: Ability unlocked, step 6 | Petrifying Bola: 1 AP upgrade, step 7 | Petrifying Bola: 2 AP upgrade, step 12 | Petrifying Bola: 5 AP upgrade, step 13 |
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Unlock1 / 2 / 5 AP upgrade costOrder only; no timings
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Current patch: the Oct 5, 2026 update, Oct 5, 2026, 11:05 PM UTC to today · ranked and unranked · all match average ranks
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