The Bongcloud Opening

Mystic Burst

5. Qc2 - Starting development of your actual pieces, you now deal enough damage to proc this consistently

Mystic Expansion

6. f4 - This improves your bishops to an absurd extent. More squares means more damage.

Compress Cooldown

7. e5 - Knight is your sustain tool with a built-in debuff remover on yourself, you should be spamming this in every fight (self cast OR on teammates)

Enchanter's Emblem

8. d4 - A strong defensive move into spirit comps. Alternatively, replace this with Weapon Shielding into a gun heavy comp (e.g. Vindicta + Haze + Venator + Rat King)

Healbane

9. Nf3 - Heal cut is easy to spread on Solomon and let's face it, most of your teammates aren't buying any.

Tankbuster

Built from Mystic Burst

10. fxe5 - We're out of the book now, we've developed our core pieces and we're ready to deal some real damage.

Greater Expansion

Built from Mystic Expansion

14. Bg5 - Threaten mate in every fight by making all of your pieces massive and threatening. More squares = more targets hit.

Spirit Rend

15. g4 - Even more spirit shred and your gun spike means you can do even more damage. Spam headshots on tanks late game for maximum throughput.

Mystic Slow

16. Nbd2 - Pin all their pawns in place by reapplying this constantly.

Spirit Resilience

(Optional) 17. Bf1 - Most teams are going to hit you with more spirit than anything, replace this with a different 3200 if needed.

Escalating Exposure

Built from Mystic Vulnerability

18. Rxf1 - You have so many bishop moves at this point that you'll max this out in no time.

Lightning Scroll

Built from Mystic Slow

19. cxd4 - Your ult has 5 chances to actually hit someone, meaning you're almost always going to land a stun that leads into your next Queen hit for insane damage.

Spellbreaker

23. b4 - Even more spirit resist + debuff resist (in case you're being silenced to prevent 2 usage)

Boundless Spirit

24. a3 - Straight up damage.

Divine Barrier

25. b5 - You already have a fairly strong dispel, but this helps with silences and gives you even more ways to save your pawns (teammates).

Refresher

26. a4 - Promote a second queen.

Echo Shard

27. Bxe7 - Imbue on 2 for support, imbue on 3 for evil permaroot teamfight nonsense.

Superior Duration

28. Qxg6 - This doesn't give you extra moves but increases the duration on all your shred, roots, and stuns.

Transcendent Cooldown

Built from Superior Cooldown

29. g5 - Really good if you pick up items with cooldowns - notably Spellbreaker, Spirit Burn, Vortex Web, Divine Barrier. This is the endgame support option.

Dispel Magic

In case your 2 dispel isn't enough (e.g. Silence), this is a second option.

Bullet Resilience

Brainless anti-gun. Useful into sustained gun damage characters (e.g. Rat King)

Metal Skin

Anti-Haze.

Fortitude

Pure HP option, good if you go jungling.

Juggernaut

Built from Enduring Speed

One of the best anti-gun items in the game, slowing fire rate is insanely powerful against most gun carries (and some spirit carries too)

Mystic Shot

If you're building Spirit and just want some extra damage on your shots in between Bishop moves this is a great choice.

Ballistic Enchantment

Built from Mystic Expansion

Even more squares on Bishops means even more spirit shred. Can also imbue on 4 for teamfight damage.

Headhunter

Solid healing item and extra damage on headshots which are relatively easy to hit.

Sharpshooter

Built from High-Velocity Rounds

You're going to be quite far away, this is the best raw gun damage item you can get.

Weighted Shots

Your buildup is honestly insane, use this to keep people in place for a 3->4->1->1 combo

Crippling Headshot

The best single-shot shred in the game, this can set up even more damage.

Spiritual Overflow

Empowers all of your other abilities, not super high value but a good hybrid option late game.